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Using a Grignard reaction, show how you could prepare each

Chapter 13, Problem 13.38

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QUESTION:

Using a Grignard reaction, show how you could prepare each of the following alcohols: OH (a) OH (b) OH (c) OH (d)

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QUESTION:

Using a Grignard reaction, show how you could prepare each of the following alcohols: OH (a) OH (b) OH (c) OH (d)

ANSWER:

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(a) Cyclohexyl magnesium bromide reacts with the formaldehyde which contains only one carbon, one oxygen, and two hydrogen atoms. This extends the carbon skeleton by one carbon and opens up the formaldehyde carbonyl, producing a primary alkoxide followed by the acid hydrolysis gives the required alcohol.

                         

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