Solution Found!
ns: O OH 1) MeMgBr 2) H2O (a) HO OH 1) Excess MeMgBr 2)
Chapter 13, Problem 13.5(choose chapter or problem)
QUESTION:
ns: O OH 1) MeMgBr 2) H2O (a) HO OH 1) Excess MeMgBr 2) H2O (b) O O
Questions & Answers
QUESTION:
ns: O OH 1) MeMgBr 2) H2O (a) HO OH 1) Excess MeMgBr 2) H2O (b) O O
ANSWER:Step 1 of 7
(a) Mechanism:
In the first step, the carbon on the methyl Grignard group (which carries a full negative charge) acts as a nucleophile and attacks the electrophilic carbon of the ketones carbonyl group. This pushes the double bond elections up onto the oxygen of the ketone, forming a secondary alkoxide.