Solution Found!
Propose an efficient synthesis for each of
Chapter 13, Problem 13.52(choose chapter or problem)
Propose an efficient synthesis for each of the following transformations: H O O (a) H O (b) H O O (c) H O (d) Cl H O (e) Cl O (f) O (g) OH (h) (i) OH (j) OH (k) H O OH (l) O (m) O (n) O HO (o) O (p) O OH (q) H Br O (r) OH (s)
Questions & Answers
QUESTION:
Propose an efficient synthesis for each of the following transformations: H O O (a) H O (b) H O O (c) H O (d) Cl H O (e) Cl O (f) O (g) OH (h) (i) OH (j) OH (k) H O OH (l) O (m) O (n) O HO (o) O (p) O OH (q) H Br O (r) OH (s)
ANSWER:Step 1 of 20
(a)
The starting material is benzaldehyde, and the resulting product contains one extra carbon atom than the starting material. There is a formation of a carbon-carbon bond. This reaction can be done using a Grignard reagent. The reaction uses methyl magnesium bromide to get the methyl group. The resulting alcohol then oxidized to give the product.