Solution Found!
Draw the product obtained when each of the following
Chapter 22, Problem 22.71(choose chapter or problem)
Draw the product obtained when each of the following compounds is heated in the presence of a base to give an aldol condensation: O (a) H O (b) H O (c)
Questions & Answers
QUESTION:
Draw the product obtained when each of the following compounds is heated in the presence of a base to give an aldol condensation: O (a) H O (b) H O (c)
ANSWER:Step 1 of 4
Recall that the protons located on a carbon adjacent to carbonyl (“alpha protons”) are unusually acidic, as the resulting conjugation base is resonance-stabilized. This conjugate base (known as an enolate) can act as a nucleophile and attack another molecule of starting material at the electrophilic carbonyl carbon. This resulting alcohol can then be dehydrated under the hot, basic reaction conditions. This is a general description of an aldol condensation reaction.