A histidine side chain is known to play an important role in the catalytic mechanism of
Chapter 0, Problem 2-10(choose chapter or problem)
A histidine side chain is known to play an important role in the catalytic mechanism of an enzyme; however, it is not clear whether histidine is required in its protonated (charged) or unprotonated (uncharged) state. To answer this question you measure enzyme activity over a range of pH, with the results shown in Figure Q21. Which form of histidine is required for enzyme activity?
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