One important role of Fas and Fas ligand is to mediate the elimination of tumor cells by
Chapter 0, Problem 18-3(choose chapter or problem)
One important role of Fas and Fas ligand is to mediate the elimination of tumor cells by killer lymphocytes. In a study of 35 primary lung and colon tumors, half the tumors were found to have amplified and overexpressed a gene for a secreted protein that binds to Fas ligand. How do you suppose that overexpression of this protein might contribute to the survival of these tumor cells? Explain your reasoning.
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