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Nicotine, a habit-forming compound found in tobacco, can be protonated twice: nicotine

Organic Chemistry | 6th Edition | ISBN: 9781936221349 | Authors: Marc Loudon, Jim Parise ISBN: 9781936221349 461

Solution for problem 3.23 Chapter 3.4

Organic Chemistry | 6th Edition

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Organic Chemistry | 6th Edition | ISBN: 9781936221349 | Authors: Marc Loudon, Jim Parise

Organic Chemistry | 6th Edition

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Problem 3.23

Nicotine, a habit-forming compound found in tobacco, can be protonated twice: nicotine CH3 .. .. H H H3O H2O H2O H3O N N CH3 .. N N H + CH3 N N + + B BH pKa = 8.02 BH2 pKa = 3.13 (a) Using intuition gained from this section, and using the pKa values shown above, sketch on the same set of axes, without performing any calculations, plots of fB, fBH, and fBH2 over the pH range 1 to 10. (b) At what pH do you think fBH is a maximum? Explain. (c) What form of nicotine is present in greatest amount if a small amount of nicotine is dissolved in blood?

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Chemistry Notes Chapter 10 and 11 Week 9 10.3 Vocabulary ● Valence bond theory: describes bonds as being formed by overlap of partially filled valence orbitals ● Hybrid orbitals: orbitals obtained by mixing two or more atomic orbitals on the same central atom Important to Know: ● Hybrid orbitals are pictured as elongated with small lobe missing ○ ● Sp hybrid orbitals ● ● Shape of hybrid orbitals (green) ○ ● Hybrid orbitals can hold lone pairs ○ Hybrid orbitals of central atoms with steric number 5 or 6 involve d

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Chapter 3.4, Problem 3.23 is Solved
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Textbook: Organic Chemistry
Edition: 6
Author: Marc Loudon, Jim Parise
ISBN: 9781936221349

Organic Chemistry was written by and is associated to the ISBN: 9781936221349. The full step-by-step solution to problem: 3.23 from chapter: 3.4 was answered by , our top Chemistry solution expert on 03/16/18, 03:35PM. The answer to “Nicotine, a habit-forming compound found in tobacco, can be protonated twice: nicotine CH3 .. .. H H H3O H2O H2O H3O N N CH3 .. N N H + CH3 N N + + B BH pKa = 8.02 BH2 pKa = 3.13 (a) Using intuition gained from this section, and using the pKa values shown above, sketch on the same set of axes, without performing any calculations, plots of fB, fBH, and fBH2 over the pH range 1 to 10. (b) At what pH do you think fBH is a maximum? Explain. (c) What form of nicotine is present in greatest amount if a small amount of nicotine is dissolved in blood?” is broken down into a number of easy to follow steps, and 113 words. This full solution covers the following key subjects: . This expansive textbook survival guide covers 239 chapters, and 1693 solutions. This textbook survival guide was created for the textbook: Organic Chemistry, edition: 6. Since the solution to 3.23 from 3.4 chapter was answered, more than 230 students have viewed the full step-by-step answer.

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Nicotine, a habit-forming compound found in tobacco, can be protonated twice: nicotine