The reaction given in Fig. P18.82 on p. 943, used to prepare the drug mephenesin (a

Chapter 18, Problem 18.82

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The reaction given in Fig. P18.82 on p. 943, used to prepare the drug mephenesin (a skeletal muscle relaxant), appears to be a simple Williamson ether synthesis. During this reaction, a precipitate of NaCl forms after only about 10 minutes, but a considerably longer reaction time is required to obtain a good yield of mephenesin. Taking these facts into account, suggest a mechanism for this reaction. (Hint: See Sec. 11.8.)

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