Acetolactate synthase is another TPP-requiring enzyme. It, too, catalyzes the
Chapter 24, Problem 9(choose chapter or problem)
Acetolactate synthase is another TPP-requiring enzyme. It, too, catalyzes the decarboxylation of pyruvate, but it transfers the resulting acyl group to another molecule of pyruvate, forming acetolactate. This is the first step in the biosynthesis of the amino acids valine and leucine. Propose a mechanism for this reaction.
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