TPP is a coenzyme for transketolase, the enzyme that catalyzes the conversion of a

Chapter 24, Problem 11

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TPP is a coenzyme for transketolase, the enzyme that catalyzes the conversion of a ketopentose (xylulose-5-phosphate) and an aldopentose (ribose-5-phosphate) into an aldotriose ( glyceraldehyde-3-phosphate) and a ketoheptose (sedoheptulose-7-phosphate). Notice that the total number of carbons in the reactants and products is the same (5 + 5 = 3 + 7) . Propose a mechanism for this reaction.

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