Alcohols undergo an oxidation reaction to yield carbonyl compounds on treatment with

Chapter 4, Problem 4.62

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Alcohols undergo an oxidation reaction to yield carbonyl compounds on treatment with CrO3. For example, 2-tert-butylcyclohexanol gives 2-tert-butylcyclohexanone. If axial OH groups are generally more reactive than their equatorial isomers, which do you think reacts faster, the cis isomer of 2-tert-butylcyclohexanol or the trans isomer? Explain. 2-tert-Butylcyclohexanol OH C(CH3)3 2-tert-Butylcyclohexanone O

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