Solved: Aprobarbital, a barbiturate once used in treating insomnia, is synthesized in
Chapter 22, Problem 22.32(choose chapter or problem)
Aprobarbital, a barbiturate once used in treating insomnia, is synthesized in three steps from diethyl malonate. Show how you would synthesize the necessary dialkylated intermediate, and then propose a mechanism for the reaction of that intermediate with urea to give aprobarbital. H2N NH2 C O Aprobarbital
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