Solved: The Favorskii reaction involves treatment of an a-bromo ketone with base to

Chapter 22, Problem 22.50

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The Favorskii reaction involves treatment of an a-bromo ketone with base to yield a ring-contracted product. For example, reaction of 2-bromocyclohexanone with aqueous NaOH yields cyclopentanecarboxylic acid. Propose a mechanism. O Br CO2H 1. NaOH 2. H3O+

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