In step 2 of the citric acid cycle (Figure 29.12), cis-aconitate reacts with water to
Chapter 29, Problem 29.41(choose chapter or problem)
In step 2 of the citric acid cycle (Figure 29.12), cis-aconitate reacts with water to give (2R,3S)-isocitrate. Does ]OH add from the Re face of the double bond or from the Si face? What about ]H? Does the addition of water occur with syn or anti geometry? H2O cis-Aconitate (2R,3S)-Isocitrate H OH H CO2 CO2 O2C H CO2 CO2 O2
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