Solved: The primary fate of acetyl CoA under normal metabolic conditions is degradation
Chapter 29, Problem 29.43(choose chapter or problem)
The primary fate of acetyl CoA under normal metabolic conditions is degradation in the citric acid cycle to yield CO2. When the body is stressed by prolonged starvation, however, acetyl CoA is converted into compounds called ketone bodies, which can be used by the brain as a temporary fuel. Fill in the missing information indicated by the four question marks in the following biochemical pathway for the synthesis of ketone bodies from acetyl CoA: HSCoA H2O Acetyl CoA Acetoacetyl CoA Acetoacetate ? ? ? ? 3-Hydroxybutyrate Ketone bodies 2 CH3CSCoA O CH3CCH2CSCoA O O Acetoacetate CH3CCH2CO O O Acetone CH3CCH3 O 3-Hydroxybutyrate CH3CHCH2CO OH O
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