Pyridine is half protonated in aqueous phosphate buffer at pH 5.2. If you mix 45 mL of

Chapter 10, Problem 10-63

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Pyridine is half protonated in aqueous phosphate buffer at pH 5.2. If you mix 45 mL of phosphate buffer with 55 mL of methanol, the buffer must have a pH of 3.2 to half protonate pyridine. Suggest a reason why.

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