Solved: Fluoride ion is usually a poor leaving group because it is not very polarizable
Chapter 0, Problem 17-21(choose chapter or problem)
Fluoride ion is usually a poor leaving group because it is not very polarizable. Fluoride serves as the leaving group in the Sanger reagent (2,4-dinitrofluorobenzene), used in the determination of peptide structures (Chapter 24). Explain why fluoride works as a leaving NO2 activates positions ortho and para NO2 Cl Cl NO2 activated Cl NO2 not activated (Continued)
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