Solved: A common illicit synthesis of methamphetamine involves an interesting variation
Chapter 0, Problem 17-67(choose chapter or problem)
A common illicit synthesis of methamphetamine involves an interesting variation of the Birch reduction. A solution of ephedrine in alcohol is added to liquid ammonia, followed by several pieces of lithium metal. The Birch reduction usually reduces the aromatic ring (Section 17-14C), but in this case it eliminates the hydroxyl group of ephedrine to give methamphetamine. Propose a mechanism, similar to that for the Birch reduction, to explain this unusual course of the reaction.
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