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Clinical Trial of Lipitor Lipitor is the trade name of the

Elementary Statistics | 12th Edition | ISBN: 9780321836960 | Authors: Mario F. Triola

Problem 19BSC Chapter 11.3

Elementary Statistics | 12th Edition

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Elementary Statistics | 12th Edition | ISBN: 9780321836960 | Authors: Mario F. Triola

Elementary Statistics | 12th Edition

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Problem 19BSC

Problem  19BSC

Clinical Trial of Lipitor Lipitor is the trade name of the drug atorvastatin, which is used to reduce cholesterol in patients. (Until its patent expired in 2011, this was the largest-selling drug in the world, with annual sales of $13 billion.) Adverse reactions have been studied in clinical trials, and the table below summarizes results for infections in patients from different treatment groups (based on data from Parke-Davis). Use a 0.01 significance level to test the claim that getting an infection is independent of the treatment. Does the atorvastatin treatment appear to have an effect on infections?

 

Placebo

Atorvastatin 10 mg

Atorvastatin 40 mg

Atorvastatin 80 mg

Infection

27

89

8

7

No Infection

243

774

71

87

Step-by-Step Solution:

Solution  19BSC

Step 1 of 1</p>

We are given a data set of infections among people given different groups of treatments. We have to test the claim that getting an infection is independent of the treatment.

Step 1: To test the claim we need to fulfil certain assumptions.

1. We assume that the sample has been randomly selected because of the structure of the study.

2. The results are tabulated as frequencies.

3. The expected frequencies are more than five in every column.

Step 2 : We will define hypothesis as below

= Getting an infection is an independent of the treatment.

= Getting an infection is not an independent of the treatment.

Step 3 of 4

Chapter 11.3, Problem 19BSC is Solved
Step 4 of 4

Textbook: Elementary Statistics
Edition: 12th
Author: Mario F. Triola
ISBN: 9780321836960

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