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DNA Ligase: Key to Joining Okazaki Fragments in Replication
Chapter 9, Problem 1(choose chapter or problem)
Figure 9.10 You isolate a cell strain in which the joining together of Okazaki fragments is impaired and suspect that a mutation has occurred in an enzyme found at the replication fork. Which enzyme is most likely to be mutated?
Questions & Answers
QUESTION:
Figure 9.10 You isolate a cell strain in which the joining together of Okazaki fragments is impaired and suspect that a mutation has occurred in an enzyme found at the replication fork. Which enzyme is most likely to be mutated?
ANSWER:
Step 1 of 2
DNA ligase is most likely to be mutated in a cell strain where the joining together of Okazaki fragments is impaired.
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DNA Ligase: Key to Joining Okazaki Fragments in Replication
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Discover the role of Okazaki fragments in DNA replication and the importance of DNA Ligase in ensuring their correct joining. Learn how a malfunction in this enzyme might disrupt the formation of continuous DNA strands on the lagging strand.