Solution Found!
Malonate \(\left({ }^{-} \mathrm{OOC}-\mathrm{CH}_{2}-\mathrm{COO}^{-}\right)\) is an extremely effective competitive inhibitor of the citric acid cycle. Which enzyme do you think malonate inhibits? Explain.
Chapter 23, Problem 23.70(choose chapter or problem)
Malonate \(\left({ }^{-} \mathrm{OOC}-\mathrm{CH}_{2}-\mathrm{COO}^{-}\right)\) is an extremely effective competitive inhibitor of the citric acid cycle. Which enzyme do you think malonate inhibits? Explain.
Questions & Answers
QUESTION:
Malonate \(\left({ }^{-} \mathrm{OOC}-\mathrm{CH}_{2}-\mathrm{COO}^{-}\right)\) is an extremely effective competitive inhibitor of the citric acid cycle. Which enzyme do you think malonate inhibits? Explain.
ANSWER:Step 1 of 3
Malonate is a competitive inhibitor of the citric acid cycle, specifically inhibiting the enzyme succinate dehydrogenase.
Succinate dehydrogenase is an enzyme involved in the citric acid cycle and is responsible for the conversion of succinate to fumarate while simultaneously participating in the electron transport chain