A chronic alcoholic requires a much larger dose of ethanol as an antidote to methanol poisoning than does a nonalcoholic patient. Suggest a reason why a larger dose of the competitive inhibitor is required for an alcoholic.
Step 1 of 3
An alcoholic has more alcohol dehydrogenase so more ethanol is needed to tie up this larger amount of enzyme. The patient is given intravenous infusions of dilute ethanol. The ADH enzyme is swamped by all the ethanol; allowing time for the kidneys to excrete most of the methanol before it can be oxidized to formic acid.
Textbook: Organic Chemistry
Author: L.G. Wade Jr
Organic Chemistry was written by and is associated to the ISBN: 9780321768414. Since the solution to 7P from 11 chapter was answered, more than 306 students have viewed the full step-by-step answer. This full solution covers the following key subjects: alcoholic, larger, dose, methanol, chronic. This expansive textbook survival guide covers 25 chapters, and 1336 solutions. This textbook survival guide was created for the textbook: Organic Chemistry, edition: 8. The answer to “A chronic alcoholic requires a much larger dose of ethanol as an antidote to methanol poisoning than does a nonalcoholic patient. Suggest a reason why a larger dose of the competitive inhibitor is required for an alcoholic.” is broken down into a number of easy to follow steps, and 37 words. The full step-by-step solution to problem: 7P from chapter: 11 was answered by , our top Chemistry solution expert on 05/06/17, 06:41PM.