A clinical trial was conducted to determine if a certain

Chapter , Problem 5.53

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A clinical trial was conducted to determine if a certain type of inoculation has an effect on the incidence of a certain disease. A sample of 1000 rats was kept in a controlled environment for a period of 1 year, and 500 of the rats were given the inoculation. In the group not inoculated, there were 120 incidences of the disease, while 98 of the rats in the inoculated group contracted it. If p1 is the probability of incidence of the disease in uninoculated rats and p2 the probability of incidence in inoculated rats, compute a 90% confi- dence interval for p1 p2.

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