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Aquaporins exclude passage of hydronium ions (H30+). But

Chapter 0, Problem 7.2

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QUESTION:

Aquaporins exclude the passage of hydronium ions (\({{\rm{H}}_{\rm{3}}}{{\rm{0}}^ + }\)). But recent research has revealed a role for some aquaporins in fat metabolism, in which they allow passage of glycerol, a three-carbon alcohol (see Figure 5.11), as well as \({{\rm{H}}_{\rm{2}}}{\rm{0}}\). Since \({{\rm{H}}_{\rm{3}}}{{\rm{0}}^ + }\) is much closer in size to water than is glycerol, what do you suppose is the basis of this selectivity?

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QUESTION:

Aquaporins exclude the passage of hydronium ions (\({{\rm{H}}_{\rm{3}}}{{\rm{0}}^ + }\)). But recent research has revealed a role for some aquaporins in fat metabolism, in which they allow passage of glycerol, a three-carbon alcohol (see Figure 5.11), as well as \({{\rm{H}}_{\rm{2}}}{\rm{0}}\). Since \({{\rm{H}}_{\rm{3}}}{{\rm{0}}^ + }\) is much closer in size to water than is glycerol, what do you suppose is the basis of this selectivity?

ANSWER:

 

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Given data:

Aquaporins exclude the passage of hydronium ions (\({{\rm{H}}_{\rm{3}}}{{\rm{0}}^ + }\)). But recent research has revealed a role for some aquaporins in fat metabolism, in which they allow passage of glycerol, three-carbon alcohol (see Figure 5.11), as well as \({{\rm{H}}_{\rm{2}}}{\rm{0}}\). \({{\rm{H}}_{\rm{3}}}{{\rm{0}}^ + }\) is much closer in size to water 

than is glycerol.

                                                                     

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