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Bioreactor production of antibodies. Benchtop bioreactors
Chapter 13, Problem 62E(choose chapter or problem)
Bioreactor production of antibodies. Benchtop bioreactors are used to produce antibodies for anti-cancer drugs. Engineers calibrate bioreactors in order to maximize production. The African Journal of Biotechnology (Dec. 2011) published a study designed to achieve a high percentage of antibody production from a bioreactor. The variable of interest was the natural logarithm of the number of viable cells produced in a bioreactor run. Data were collected for a sample of four bioreactor runs every 6 hours for 20 consecutive time periods. These data (simulated from information provided in the article) are listed in the accompanying table. Engineers have specified the following for the bioreactor runs: target mean = 6.3, LSL = 5.9, and USL = 6.5. Run a complete capability analysis on the data. How would you categorize the performance of the process?
Questions & Answers
QUESTION:
Bioreactor production of antibodies. Benchtop bioreactors are used to produce antibodies for anti-cancer drugs. Engineers calibrate bioreactors in order to maximize production. The African Journal of Biotechnology (Dec. 2011) published a study designed to achieve a high percentage of antibody production from a bioreactor. The variable of interest was the natural logarithm of the number of viable cells produced in a bioreactor run. Data were collected for a sample of four bioreactor runs every 6 hours for 20 consecutive time periods. These data (simulated from information provided in the article) are listed in the accompanying table. Engineers have specified the following for the bioreactor runs: target mean = 6.3, LSL = 5.9, and USL = 6.5. Run a complete capability analysis on the data. How would you categorize the performance of the process?
ANSWER:
Step 1 of 3
Use MINITAB to construct process capability.
MINITAB procedure:
Step 1: Choose Stat > Quality Tools > Capability Analysis > Normal.