An article in Mathematical Biosciences [“Influence of

Chapter 4, Problem 152E

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QUESTION:

An article in Mathematical Biosciences [“Influence of Delayed Viral Production on Viral Dynamics in HIV-1 Infected Patients” (1998, Vol.152(2), pp. 143–163)] considered the time delay between the initial infection by immunodeficiency virus type 1 (HIV-1) and the formation of productively infected cells. In the simulation model, the time delay is approximated by a gamma distribution with parameters r = 4 and \(1 / \lambda=0.25\) days. Determine the following:

(a) Mean and variance of time delay

(b) Probability that a time delay is more than half a day

(c) Probability that a time delay is between one-half and one day

Equation transcription:

Text transcription:

1 / lambda=0.25

Questions & Answers

QUESTION:

An article in Mathematical Biosciences [“Influence of Delayed Viral Production on Viral Dynamics in HIV-1 Infected Patients” (1998, Vol.152(2), pp. 143–163)] considered the time delay between the initial infection by immunodeficiency virus type 1 (HIV-1) and the formation of productively infected cells. In the simulation model, the time delay is approximated by a gamma distribution with parameters r = 4 and \(1 / \lambda=0.25\) days. Determine the following:

(a) Mean and variance of time delay

(b) Probability that a time delay is more than half a day

(c) Probability that a time delay is between one-half and one day

Equation transcription:

Text transcription:

1 / lambda=0.25

ANSWER:

Solution:

Step 1 of 4:

The time delay is approximated by a gamma distribution with parameters r=4 and  = 0.25.

  1. We have to find the mean and variance of the time delay.

  1. We have to find the probability that a time delay is more than half a day.

  1. We have to find the probability that a time delay is between one- half and one day.


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