Carbon monoxide is toxic because it binds more strongly to iron in hemoglobin (Hb) than

Chapter 21, Problem 21.93

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Carbon monoxide is toxic because it binds more strongly to iron in hemoglobin (Hb) than does O2. Consider the following reactions and approximate standard free energy changes: Hb 1 O2 h HbO2 DG 5 270 kJ Hb 1 CO h HbCO DG 5 280 kJ Using these data, estimate the equilibrium constant value at 258C for the following reaction: HbO2 1 COmHbCO 1 O2

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