Thiamin diphosphate (TPP), a derivative of vitamin B1

Chapter 2, Problem 2

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Thiamin diphosphate (TPP), a derivative of vitamin B1 required for glucose metabolism, is a weak acid that can be deprotonated by a base. Assign formal charges to the appropriate atoms in both TPP and its deprotonation product.

Equation Transcription:

Text Transcription:

pK_a=18

O-P-O-POCH_2CH_2

CH_3

CH_3

NH_2

O-P-O-POCH_2CH_2

CH_3

NH_2

CH_3

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