Evidence that cleavage of 1,2-diols by HIO4 occurs through

Chapter 8, Problem 8

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Evidence that cleavage of 1,2-diols by \(\mathrm {HIO_4}\) occurs through a five membered cyclic periodate intermediate is based on kinetic data—the measurement of reaction rates. When diols A and B were prepared and the rates of their reaction with \(\mathrm {HIO_4}\) were measured, it was found that diol A cleaved approximately 1 million times faster than diol B. Make molecular models of A and B and of potential cyclic periodate intermediates, and then explain the kinetic results

Equation Transcription:

Text Transcription:

HIO_4

HIO_4

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