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A solution of 0.50 g of (-)@epinephrine (see Figure 5-16) dissolved in 10.0 mL of dilute

Chapter 5, Problem PROBLEM 5-9

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QUESTION:

A solution of 0.50 g of (-)@epinephrine (see Figure 5-16) dissolved in 10.0 mL of dilute aqueous HCl was placed in a 20-cm polarimeter tube. Using the sodium D line, the rotation was found to be -5.1 at 25 C. Determine the specific rotation of epinephrine.

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QUESTION:

A solution of 0.50 g of (-)@epinephrine (see Figure 5-16) dissolved in 10.0 mL of dilute aqueous HCl was placed in a 20-cm polarimeter tube. Using the sodium D line, the rotation was found to be -5.1 at 25 C. Determine the specific rotation of epinephrine.

ANSWER:

Step 1 of 3

Specific rotation can be calculated using the expression given below:

,

where  is the observed rotation in polarimeter.

 is the concentration of the given compound in

 is the path length in .

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