Putting It Together: Drug Side Effects In placebocontrolled clinical trials for the drug

Chapter 5, Problem 54

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Putting It Together: Drug Side Effects In placebocontrolled clinical trials for the drug Viagra, 734 subjects received Viagra and 725 subjects received a placebo (subjects did not know which treatment they received). The table in the next column summarizes reports of various side effects that were reported.Adverse Effect Viagra (n 734) Placebo (n 725)Headache 117 29Flushing 73 7Dyspepsia 51 15Nasal congestion 29 15Urinary tract infection 22 15Abnormal vision 22 0Diarrhea 22 7Dizziness 15 7Rash 15 7(a) Is the variable adverse effect qualitative or quantitative?(b) Which type of graph would be appropriate to display theinformation in the table? Construct the graph.(c) What is the estimated probability that a randomly selectedsubject from the Viagra group reported experiencingflushing? Would this be unusual?(d) What is the estimated probability that a subject receiving aplacebo would report experiencing flushing? Would this beunusual?(e) If a subject reports flushing after receiving a treatment, whatmight you conclude?(f ) What type of experimental design is this?

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