Monomeric single-pass transmembrane proteins span a membrane with a single helix that

Chapter 0, Problem 10-7

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Monomeric single-pass transmembrane proteins span a membrane with a single helix that has characteristic chemical properties in the region of the bilayer. Which of the three 20-amino-acid sequences listed below is the most likely candidate for such a transmembrane segment? Explain the reasons for your choice. (See back of book for one-letter amino acid code; FAMILY VW is a convenient mnemonic for hydrophobic amino acids.) A. I T L I Y F G V M A G V I G T I L L I S B. I T P I Y F G P M A G V I G T P L L I S C. I T E I Y F G R M A G V I G T D L L I S

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