(a) Give the products that result from the hydrolysis of the phosphate ester group of

Chapter 25, Problem 25.28

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(a) Give the products that result from the hydrolysis of the phosphate ester group of phosphoenolpyruvate (PEP), an important compound in the glycolysis pathway. OPO3 2C CO CH 2 2 phosphoenolpyruvate (PEP) (b) The DG for the hydrolysis of PEP is 261.9 kJ mol1 (14.8 kcal mol1 ), which puts it well into the category of a high-energy compound. Most phosphate esters have a DG for hydrolysis of about 213.8 kJ mol1 (3.3 kcal mol1 ). Explain why the hydrolysis of PEP releases much more energy than the hydrolysis of an ordinary phosphate ester.

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