Solved: There are two kinds of aldolases. Class I aldolases are found in animals and

Chapter 22, Problem 36

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There are two kinds of aldolases. Class I aldolases are found in animals and plants, whereas class II aldolases are found in fungi, algae, and some bacteria.Only class I aldolases form an imine. Class II aldolases have a metal ion (Zn2 + ) at the active site. The mechanism for catalysis by class I aldolases wasdescribed in Section 22.13. Propose a mechanism for catalysis by class II aldolases.

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