Vancomycin is an important antibiotic. It is isolated from the bacterium Streptomy-ces
Chapter 24, Problem 24.38(choose chapter or problem)
Vancomycin is an important antibiotic. It is isolated from the bacterium Streptomy-ces orientalis and functions by inhibiting bacterial mucopeptide synthesis. It is alast line of defense against the resistant Staph organisms that are now common inhospitals. (a) Suggest reasonable precursors and show how the bonds could be formed (theactual reagents used have not been introduced, but they work in a similar wayto those you know).(b) Give reagents for this reaction and suggest the mechanism. (c) Show these two isomers.(II) was then converted to (III).(d) Suggest reagents to accomplish this transformation.
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