Epibatidine, a colorless oil isolated from the skin of the

Chapter 23, Problem 23.28

(choose chapter or problem)

Epibatidine, a colorless oil isolated from the skin of the Ecuadorian poison frog Epipedobates tricolor, has several times the analgesic potency of morphine. It is the fi rst chlorine-containing, nonopioid (nonmorphine-like in structure) analgesic ever isolated from a natural source. Cl N H N Epibatidine (a) Which of the two nitrogen atoms of epibatidine is the more basic? (b) Mark all chiral centers in this molecule.

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