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RECALL What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and \(\alpha\)-ketoglutarate dehydrogenase?

Chapter 19, Problem 22

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QUESTION:

What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and \(\alpha\) -ketoglutarate dehydrogenase?

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QUESTION:

What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and \(\alpha\) -ketoglutarate dehydrogenase?

ANSWER:

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The enzyme that catalyzes the reaction of pyruvate and lipoamide to generate acetylated lipoamide and carbon dioxide is pyruvate dehydrogenase.

The \(\alpha\)-ketoglutarate dehydrogenase complex constitutes an enzyme complex that is prominent for its role in the citric acid cycle.

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