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Beriberi is a disease caused by a deficiency of vitamin \(\mathrm{B}_{1}\) (thiamine) in the diet. Thiamine is the precursor of thiamine pyrophosphate. In view of what you have learned in this chapter, why is it not surprising that alcoholics tend to develop this disease?

Chapter 17, Problem 34

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QUESTION:

Beriberi is a disease caused by a deficiency of vitamin \(\mathrm{B}_{1}\) (thiamine) in the diet. Thiamine is the precursor of thiamine pyrophosphate. In view of what you have learned in this chapter, why is it not surprising that alcoholics tend to develop this disease?

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QUESTION:

Beriberi is a disease caused by a deficiency of vitamin \(\mathrm{B}_{1}\) (thiamine) in the diet. Thiamine is the precursor of thiamine pyrophosphate. In view of what you have learned in this chapter, why is it not surprising that alcoholics tend to develop this disease?

ANSWER:

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Unsurprisingly, alcoholics tend to develop beriberi, a disease caused by a deficiency of vitamin \({B_1}\) (thiamine), due to several factors related to alcohol consumption and its effects on thiamine metabolism.

Here are some reasons why alcoholics are prone to thiamine deficiency and subsequent beriberi:

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