Rank the following compounds in decreasing order of their reactivity toward the SN2 reactionwith sodium ethoxide in ethanol.
methyl chloride tert-butyl iodide neopentyl bromide
isopropyl bromide methyl iodide ethyl chloride
Factors that affect the rate of reactions are as follows:
1. Nature of leaving group
2. Nature of the substrate
Weak bases are good leaving groups. In halogens, the leaving group order is as follows:
The substrate with less steric hindrance has a high reactivity towards the reaction.
The substrate reactivity order is as follows:
Methyl halides are most reactive towards the reactions. So, among the given compounds, methyl halides are methyl chloride and methyl iodide.
Methyl iodide is most reactive towards the reaction than methyl...