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Draw the pH–activity profile for an enzyme that has one

Chapter 23, Problem 24P

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QUESTION:

Problem 24P

Draw the pH–activity profile for an enzyme that has one catalytic group at the active site:

a. the catalytic group is a general-acid catalyst with a pKa = 5.6.

b. the catalytic group is a general-base catalyst with a pKa = 7.2.

Questions & Answers

QUESTION:

Problem 24P

Draw the pH–activity profile for an enzyme that has one catalytic group at the active site:

a. the catalytic group is a general-acid catalyst with a pKa = 5.6.

b. the catalytic group is a general-base catalyst with a pKa = 7.2.

ANSWER:

Solution 24P

(a)

According to the given information the general acid catalyst has a

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