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A fatty acid with an even number of carbons is metabolized
Chapter 24, Problem 19P(choose chapter or problem)
A fatty acid with an even number of carbons is metabolized to acetyl-CoA, which can then
enter the citric acid cycle to be further metabolized ( Section \(25.10\) ) . A fatty acid with an
odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA.
Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are
needed to convert it into succinyl-CoA, a compound that can enter the citric acid cycle. Write
the two enzyme-catalyzed reactions and include the names of the required coenzymes.
Equation Transcription:
Text Transcription:
25.10
Questions & Answers
QUESTION:
A fatty acid with an even number of carbons is metabolized to acetyl-CoA, which can then
enter the citric acid cycle to be further metabolized ( Section \(25.10\) ) . A fatty acid with an
odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA.
Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are
needed to convert it into succinyl-CoA, a compound that can enter the citric acid cycle. Write
the two enzyme-catalyzed reactions and include the names of the required coenzymes.
Equation Transcription:
Text Transcription:
25.10
ANSWER:Solution 19P
A fatty acid with an even number of carbons is metabolized to produce acetyl-CoA. This molecule can enter the citric acid cycle, where it undergoes further degradation. A fatty acid that has an odd number of carbons is metabolized to both acetyl-CoA and one equivalent of propionyl-CoA. This second compound (propionyl-CoA) can’t enter the citric acid cycle. It first needs to be converted into succinyl-CoA, which is a