Bradykinin is a nonapeptide obtained by the partial
Chapter 28, Problem 58(choose chapter or problem)
Bradykinin is a nonapeptide obtained by the partial hydrolysis of blood serum protein. It causes a lowering of blood pressure and an increase in capillary permeability. Complete hydrolysis of bradykinin yields three proline (Pro), two arginine (Arg), two phenylalanine (Phe), one glycine (Gly), and one serine (Ser) amino acid units. The N-terminal and C-terminal units are both arginine (Arg). In a hypothetical experiment, partial hydrolysis and sequence proof reveals the following fragments: Gly-Phe-Ser-Pro; Pro-Phe-Arg; Ser-Pro-Phe; Pro-Pro-Gly; Pro-Gly-Phe; Arg-Pro-Pro; Phe-Arg. Deduce the sequence of amino acid units in bradykinin.
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