Would people with chromosomal translocations or with point

What is the main goal of the Human Genome Project?

What was the reason for sequencing the genome of a simple multicellular organism (worm)?

What is the reason for sequencing the genomes of important crops and food animals?

How are electrophoresis and computers used in DNA sequencing?

How can functional genomics speed up the design and testing of new medications?

What problem does PCR solve?

Is it likely that you carry some SNPs? Explain your answer.

Is RFLP analysis more useful for determining a DNA sequence or for identifying an individual? Explain your answer.

Distinguish between a missense mutation and a nonsense mutation.

Would deletion of three nucleotides cause a frameshift mutation? Would a deletion of five nucleotides cause a frameshift? Explain your answers.

Why would it be difficult to design a genetic test for a disease that was caused by mutations in a large gene?

Describe the results of gene amplification.

Distinguish between germ-line therapy and somatic-cell gene therapy.

What are the major likely risks and benefits of gene therapy?

How could one frameshift mutation compensate for another?

Gene amplification in cancer cells has been shown to lead to resistance to cancer-killing medications when the dose of medication is increased gradually. Starting with a high dose is a more effective way to kill cancer cells. Describe a hypothesis that explains these results.

How could gene therapy cause new genetic damage?

How could restriction enzymes be useful in gene therapy?

How could a mutation in a tRNA gene help overcome the effect of a point mutation in a gene that encodes a protein?

Would people with chromosomal translocations or with point mutations be better candidates for gene therapy? Explain your answer.

How could a mutation in a tRNA gene help overcome the effect of a nonsense mutation in a gene that encodes a protein?

Research the current status of genetic screening and counseling for cystic fibrosis, sickle-cell anemia, Tay-Sachs disease, or another common genetic disorder. Report to the class on the technology available today for your topic and the current ethical, legal, and social issues involved.