The article The Effect of Enzyme Inducing Agents on

Chapter 10, Problem 10.21

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The article The Effect of Enzyme Inducing Agents on theSurvival Times of Rats Exposed to Lethal Levels of NitrogenDioxide (Toxicology and Applied Pharmacology,1978: 169174) reports the following data on survival timesfor rats exposed to nitrogen dioxide (70 ppm) via differentinjection regimens. There were J 14 rats in each group. a. Test the null hypothesis that true average survival timedoes not depend on injection regimen against the alternativethat there is some dependence on injection regimenusing .01.b. Suppose that 100(1 )% CIs for k different parametricfunctions are computed from the same ANOVA data set.Then it is easily verified that the simultaneous confi-dence level is at least 100(1 k)%. Compute CIs withsimultaneous confidence level at least 98% for1 15(2 3 4 5 6) and 14(2 34 5) 6.We now briefly c

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