Aspirin or acctylsalicylic acid is synthesized by

Chapter 8, Problem 75AP

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 Aspirin or acetyl salicylic acid is synthesized by combining salicylic acid with acetic anhydride:

\(\begin{array}{l}\mathrm{C}_{7} \mathrm{H}_{6} \mathrm{O}_{3}+\mathrm{C}_{4} \mathrm{H}_{6} \mathrm{O}_{3} \longrightarrow \mathrm{C}_{9} \mathrm{H}_{8} \mathrm{O}_{4}+\mathrm{HC}_{2} \mathrm{H}_{3} \mathrm{O}_{2}\\\text{Salicylic acid acetic anhydride aspirin } \quad \text{ acetic acid}\end{array}\)

(a) How much salicylic acid is required to produce 0.400 g of aspirin (about the content in a tablet), assuming acetic anhydride is present in excess? (b) Calculate the amount of salicylic acid needed if only 74.9 percent of salicylic is converted to aspirin. (c) In one experiment, 9.26 g of salicylic acid react with 8.54 g of acetic anhydride. Calculate the theoretical yield of aspirin and the percent yield if only 10.9 g of aspirin are produced.

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