Write the fi nal products of the following reaction sequences.(a) O CH2 CHCCH3OPB

Chapter 18, Problem 58

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Write the fi nal products of the following reaction sequences.(a) O CH2 CHCCH3OPB NaOCH3, CH3OH, (b)CH3 CH2 CHCCH3H3COPB OKOH, CH3OH, (c)O 1. LDA, THFO B2. HCqCCCH3CH3CCH CH23-Buten-2-oneOBP(c)O 1. (CH2PCH)2CuLi, THFOB2. CH2PCHCCH3(d)1. (CH3)2CuLi, THFOB2. (CH3)2CPCHCCH3OCH3(d) Write a detailed mechanism for reaction sequence (c). (Hint: Treat the 3-butyn-2-one reagentas a Michael acceptor in the fi rst step.)

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