Januvia is the trade name for sitagliptin, a drug that increases the bodys ability to

Chapter 17, Problem 17.16

(choose chapter or problem)

Januvia is the trade name for sitagliptin, a drug that increases the bodys ability to lower blood sugar levels, and thus it was introduced in 2006 for the treatment of type 2 diabetes. (a) Explain why the fi ve-membered ring in sitagliptin is aromatic. (b) Determine the hybridization of each N atom. (c) In what type of orbital does the lone pair on each N atom reside? O N N N N F F F sitagliptin NH2 CF3

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