A published synthesis of the analgesic nabumetone uses a crossed aldol reaction to form
Chapter 24, Problem 24.32(choose chapter or problem)
A published synthesis of the analgesic nabumetone uses a crossed aldol reaction to form X. What is the structure of X? X is converted to nabumetone in one step by hydrogenation with H2 and Pd-C. (See 23.29 for another way to make nabumetone.) CHO X NaOEt CH3O EtOH nabumetone O CH3O (CH3)2C O Pd-C H2
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