The phosphorylation of -d-glucopyranose by ATP (Section 26.3) has G = 23 kJ at 298 K. HO

Chapter 26, Problem 26.24

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The phosphorylation of -d-glucopyranose by ATP (Section 26.3) has G = 23 kJ at 298 K. HO O OH HO HO OH hexokinase ATP + HO O OH HO HO O ADP + P O O O (a) Is this reaction exergonic or endergonic? (b) How would the value of G change in the absence of the enzyme hexokinase? Would it become more positive, more negative, or would it stay the same? Why? (c) Use the value for the hydrolysis of ATP to ADP (Section 26.5) to calculate G for the reaction of -d-glucopyranose with inorganic phosphate. Is this reaction exergonic or endergonic?

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