The coupling reaction of 2,6-dichloropurine with
Chapter 26, Problem 26.27(choose chapter or problem)
The coupling reaction of 2,6-dichloropurine with 1,2,3,4-tetra-O-acetyl-+-arabinofuranose takes place when the two are heated in the presence of p-toluenesulfonic acid to give the nucleoside in 75% yield. The reaction is stereoselective for the formation of the -anomer, even though the starting sugar is a mixture of anomers. Can you think of a reason for the stereoselectivity? (Hint: See Mechanism 23.3.)
Unfortunately, we don't have that question answered yet. But you can get it answered in just 5 hours by Logging in or Becoming a subscriber.
Becoming a subscriber
Or look for another answer